P Shot Before and After Care

Two Weeks Before the P Shot

• Avoid Blood Thinners — Refrain from use of excessive or unnecessary blood thinners.

• Avoid Supplements — Consider avoiding supplements that may increase bruising, such as high-dose vitamin E or fish oil.

• Plan Schedule — Make sure you allow rest after the procedure if needed.

One Week Before Priapus Shot

• Avoid NSAIDs — Use of any Nonsteroidal anti-inflammatory drugs (NSAIDs) including over-the-counter medications like Ibuprofen (Motrin, Aleve) and Aspirin, as well as prescription medications like Naproxen is not recommended, as these medications may interfere with platelet function.

• Use Acetaminophen — Use Acetaminophen (Tylenol) for pain relief, when necessary.

• Avoid Alcohol — Reduce the risk of bruising and support platelet function.

• Stay Hydrated — Drink plenty of water to optimize platelet activity and recovery.

Three Days Before the P Shot

• Notify Physician — If you have a history of genital herpes, notify the physician, who will prescribe a course of antiviral prophylactic treatment.

• Take Arnica — Take a course of Arnica Homeopathic tablets until a day after treatment to decrease the occurrence of bruising.

• Reschedule if Needed — Notify Smooth Synergy® to reschedule, If between now and your appointment, you have an active outbreak of Human Papillomavirus (HPV) or genital herpes.

• Avoid Strenuous Exercise — Light activity is fine, but avoid heavy workouts 24–48 hours before treatment.

• Groom Carefully — Shave or groom carefully if needed, but avoid irritation to the treatment area.

The Day of Your PRP Procedure

Comfort Measures:

• • Use Topical Numbing — A topical numbing cream can be applied before treatment.

  • Take Anti-Anxiety Medication if Needed — If you elect to receive anti-anxiety medicine, such as Xanax, the physician will provide it on-site.

  • Use Pro-Nox Analgesic — Pro Nox self-administered analgesic is available to reduce pain and anxiety.

Preparation & Safety Tips:

• • Eat a Light Meal — Be sure to eat a small meal prior to treatment, as blood will be drawn.

  • Arrange Transportation — If opting for anti-anxiety medication, arrange for transportation home following treatment.

  • Wear Comfortable Clothing — Loose-fitting clothes make it easier to access the treatment area and stay relaxed.

  • Stay Hydrated — Drink water before your appointment to support platelet function and overall comfort.

  • Avoid Alcohol and Caffeine — Minimizes bruising, swelling, and anxiety.

  • Bring a Support Person if Needed — Especially if you’re taking anti-anxiety medication.

  • Limit Stressful Activities — Keep the morning calm to reduce anxiety and optimize results.

P Shot After Care

Post-Procedure Safety & Activity:

• • Allow Medication to Wear Off — Allow up to two hours for anti-anxiety medication to wear off. Be sure you feel steady on your feet before engaging in any activity.

  • Shower and Cleanse — Showering and cleansing the treatment area are allowed once medication has worn off. A gentle cleanser may be used on the treatment area.

  • Avoid Strenuous Exercise — Refrain from strenuous exercise for 24 hours.

  • Monitor Symptoms — If extreme swelling or any unforeseen symptoms occur, please contact Smooth Synergy® at 212-397-0111.

Comfort Measures:

• • Use Acetaminophen — Acetaminophen may be used for discomfort. Refrain from NSAIDs (see above) for seven days.

  • Antihistamines — Antihistamines, like Benadryl and Zyrtec, may be used for minor itching.

  • Apply Ice or Cool Packs — For up to 48 hours following treatment, cool packs or ice can relieve minor discomfort and reduce swelling and bruising. Ice for a maximum of 20 minutes per hour. After 48 hours, switch to hot packs.

  • Use Arnica Gel — May be applied for bruising.

  • Stay Hydrated — Continue drinking plenty of water to support healing and platelet function.

  • Avoid Alcohol — Helps minimize bruising and swelling.

  • Wear Loose Clothing — Prevents irritation on treated areas.

  • Rest as Needed — Light activity is fine, but allow your body to recover.

Post-Treatment Expectations for the Priapus Shot

Safety and Activity:

• • Generally Safe — The P Shot is generally considered safe with minimal downtime, side effects, and recovery.

  • Return to Normal Activity — With the exception of strenuous exercise, you may return to normal activity including sexual intercourse after treatment.

Common Side Effects:

• • Minor Symptoms — Most side effects from the treatment should not be cause for alarm. Symptoms are usually minor and should subside in time, as a normal part of the healing process. They may be alleviated with simple measures, as described above.

  • Flushing — Immediately following treatment, the treatment area may appear flushed, which usually subsides within several hours.

  • Tingling, Swelling, and Soreness — Mild tingling, swelling, soreness, and tenderness on the penis may occur for up to three days.

  • Bruising — Bruising, particularly at the injection site of the penis, may last for several weeks.

When to Contact Your Provider:

• • Report Concerns — If you are concerned about any aspect of your post-treatment recovery, please call Smooth Synergy® at 212-397-0111.

  • Seek Attention for Severe Symptoms — Contact your provider if you experience significant pain, prolonged swelling, or other unusual reactions.

Additional Tips:

• • Continue Hydration — Drinking plenty of water supports healing.

  • Avoid Alcohol — Helps minimize swelling and bruising.

  • Wear Loose Clothing — Prevents irritation on treated areas.

  • Rest as Needed — Light activity is fine, but allow your body to recover.

How The P Shot Works:

• Platelet-Rich Plasma (PRP) Therapy — The P Shot uses your own platelet-rich plasma, injected into the penis, to stimulate tissue regeneration, improve blood flow, and encourage collagen remodeling. This enhances healing, sensitivity, and function over time.

Expected Priapus Shot Results:

Most men experience improved sensation on the penis immediately following the P Shot. Additionally, collagen remodeling will continue for up to six months to deliver benefits that can include:

• • Lasting Improvements in Sexual Performance

  • A Larger, Stronger, and Straighter Penis

  • Firmer, More Frequent Erections

  • Increased Circulation for a Healthier Penis

  • Increased Sensation and Pleasure

  • Enhancement of the Results of Viagra or Cialis

  • May Correct Damage from Diabetes

  • Improved Erectile Function in Cases of Injury or Trauma

  • Enhanced Tissue Health and Skin Quality

Treatment Recommendations:

• • Initial Treatment — One treatment is recommended to start.

  • Re-Evaluation — Re-evaluation is recommended after several months. Results may vary.

  • Maintenance — Some men require yearly maintenance of the procedure.

Smooth Synergy® Medical Spa & Laser Center in Manhattan, New York has over 20 years experience in the medical spa industry, giving us a distinct advantage in delivering real solutions and superior results with all of our cosmetic aesthetic treatments, including the P Shot or Priapus Shot to reverse sexual dysfunction for an improved sex life. 

What’s more, Dr. George Liakeas, Smooth Synergy® Medical Director, holds the distinction of receiving training from the creator of Vampire PRP therapy for cosmetic use, Dr. Charles Runels.

Why does this matter?

Anyone can claim that they perform the P Shot. Only physicians certified by Dr. Runels are performing PRP procedures following his carefully researched, developed and FDA-cleared protocols. 

Put simply, with something as delicate as a man’s sexual health, why wouldn’t you choose the doctor who trains the doctors?

Your sexual health and wellness is important! Call us at 212-397-0111 to find out why the P-Shot may be the answer to restore your sexual health and improve your love life.