O Shot Before and After Care

Before the O Shot

Two Weeks Before Treatment

• Avoid Blood Thinners — Refrain from use of excessive or unnecessary blood thinners.

• Avoid Supplements — Consider avoiding supplements that may increase bruising, such as high-dose vitamin E or fish oil.

• Plan Schedule — Allow rest after the procedure if needed.

One Week Before

• Avoid NSAIDs — Use of any Nonsteroidal anti-inflammatory drugs (NSAIDs) including over-the-counter medications like Ibuprofen (Motrin, Aleve) and Aspirin, as well as prescription medications like Naproxen is not recommended, as they may interfere with platelet function.

• Use Acetaminophen — Use Acetaminophen (Tylenol) for pain relief, when necessary.

• Avoid Alcohol — Reduces the risk of bruising and supports platelet function.

• Stay Hydrated — Drink plenty of water to optimize platelet activity and recovery.

Three Days Before

• Discontinue Vaginal Products — Stop use of any vaginal creams, gels, or douches.

• Notify Physician — If you have a history of genital herpes, notify the physician, who will prescribe a course of antiviral prophylactic treatment.

• Avoid Bleaching — Refrain from bleaching the vagina.

• Take Arnica — Take a course of Arnica Homeopathic tablets until a day after treatment to decrease the occurrence of bruising.

• Reschedule if Needed — Notify Smooth Synergy® to reschedule if, between now and your appointment, you are:

  • Menstruating

  • Experiencing an active outbreak of genital herpes or Human Papillomavirus (HPV) 

  • Pregnant or breastfeeding

The Day of Your O Shot Procedure

Preparation & Safety Tips:

• Bring Gynecologic Clearance — Arrive with Pap Smear / Gynecologist clearance from within the last 12 months.

• Eat a Light Meal — Be sure to eat a small meal prior to treatment.

• Stay Hydrated — Drink water before your appointment to support platelet function and overall comfort.

• Wear Comfortable Clothing — Loose-fitting clothes make it easier to access the treatment area and stay relaxed.

• Avoid Alcohol and Caffeine — Minimizes bruising, swelling, and anxiety.

Comfort Measures:

• Use Topical Numbing — A topical numbing cream can be applied before treatment.

• Take Anti-Anxiety Medication if Needed — If you elect to receive anti-anxiety medicine, such as Xanax, the physician will provide it on-site.

• Use Pro-Nox Analgesic — Pro Nox self-administered analgesic is available to reduce pain and anxiety.

• Bring a Support Person if Needed — Especially if you’re taking anti-anxiety medication.

• Limit Stressful Activities — Keep the morning calm to reduce anxiety and optimize results.

• If opting for anti-anxiety medication, arrange for transportation home following treatment.

O-Shot Aftercare

Post-Procedure Safety & Activity:

• Allow Medication to Wear Off — Allow up to two hours for anti-anxiety medication to wear off. Be sure you feel steady on your feet before engaging in any activity.

• Shower and Cleanse — Showering and cleansing the vagina is allowed once medication has worn off. A gentle cleanser may be used on the treatment area.

• Avoid Strenuous Exercise — Avoid strenuous exercise for 24 hours.

• Monitor Symptoms — If extreme swelling or any unforeseen symptoms occur, please contact Smooth Synergy® at 212-397-0111.

Comfort Measures:

• Use Acetaminophen — Acetaminophen may be used for discomfort. Refrain from NSAIDs (see above) for seven days.

• Antihistamines — Antihistamines, like Benadryl and Zyrtec, may be used for minor itching.

• Apply Ice or Cool Packs — For up to 48 hours following treatment, cool packs or ice can relieve minor discomfort and reduce swelling and bruising. Ice for a maximum of 20 minutes per hour. After 48 hours, switch to hot packs.

• Use Arnica Gel — May be applied for bruising.

• Stay Hydrated — Continue drinking plenty of water to support healing and platelet function.

• Avoid Alcohol — Helps minimize swelling and bruising.

• Wear Loose Clothing — Prevents irritation on treated areas.

• Rest as Needed — Light activity is fine, but allow your body to recover.

Post-Treatment Expectations for the O Shot

Safety and Activity:

• Generally Safe — The O Shot is noninvasive, meaning it’s typically considered safe with minimal downtime, side effects, and recovery.

• Return to Normal Activity — You may return to normal activity with the exception of strenuous exercise. Sexual intercourse is allowed after treatment.

Common Side Effects:

• Minor Symptoms — Most side effects from the treatment should not be cause for alarm. Symptoms are usually minor and should subside in time, as a normal part of the healing process. They may be alleviated with simple measures, as described above.

• Flushing — Immediately following treatment, the treatment area may appear flushed, which usually subsides within several hours.

• Tingling, Swelling, Soreness, and Tenderness — Mild tingling, swelling, soreness, and tenderness may occur for up to three days.

• Bruising — Bruising, particularly at the injection site, may last for several weeks.

When to Contact Your Provider:

• Report Concerns — If you are concerned about any aspect of your post-treatment recovery, please call Smooth Synergy® at 212-397-0111.

• Seek Attention for Severe Symptoms — Contact your provider if you experience significant pain, prolonged swelling, or other unusual reactions.

Additional Tips:

• Stay Hydrated — Drinking plenty of water supports healing.

• Avoid Alcohol — Helps minimize swelling and bruising.

• Wear Loose Clothing — Prevents irritation on treated areas.

• Rest as Needed — Light activity is fine, but allow your body to recover.

How It Works:

Platelet-Rich Plasma (PRP) Therapy — The O Shot uses your own platelet-rich plasma, injected into the vaginal tissue, to stimulate collagen remodeling, tissue regeneration, and improved blood flow. This promotes vaginal rejuvenation, increased sensitivity, and enhanced sexual and pelvic health over time.

Expected O Shot Results:

Most women will see an immediate vaginal rejuvenation benefit from the O Shot. Additionally, collagen remodeling of the vagina will continue for up to six months, delivering results that can include:

• • Improved Pelvic And Sexual Health

  • Stronger Orgasms

  • Tighter Vaginal Walls

  • Increased Lubrication In The Vagina

  • Enhanced Sensitivity

  • Relief From Dyspareunia (Painful Sex)

  • Relief From Lichen Sclerosis

  • Relief From Stress Urinary Incontinence

  • Improved Vaginal Tissue Health And Elasticity

  • Enhanced Confidence And Comfort During Sexual Activity

Treatment Recommendations:

• Initial Treatment — Following the initial treatment, schedule a treatment once a year to maintain results.

• Maintenance — Some women may benefit from more frequent treatments based on individual results and provider recommendations.

Smooth Synergy® Medical Spa & Laser Center in Manhattan, New York has over 20 years experience in the medical spa industry, giving us a distinct advantage in delivering real solutions and superior results with all of our cosmetic aesthetic treatments, including the O Shot to reverse sexual dysfunction for an improved sex life. 

What’s more, Dr. George Liakeas, Smooth Synergy® Medical Director, holds the distinction of receiving training from the creator of Vampire PRP therapy for cosmetic use, Dr. Charles Runels.

Why does this matter?

Anyone can claim that they perform the P Shot. Only physicians certified by Dr. Runels are performing PRP procedures following his carefully researched, developed and FDA-cleared protocols. 

Put simply, with something as delicate as a woman’s sexual health and wellness, why wouldn’t you choose the doctor who trains the doctors?

Smooth Synergy® Medical Spa and Laser Center is conveniently located in Manhattan, New York City and has provided compassionate, caring and effective sexual and pelvic healthcare for over 20 years. Call Smooth Synergy® at 212-397-0111 for a free consultation to find out if the O Shot and/or other vaginal rejuvenation procedures are right for you.