P-Shot: Before and After Care

The P-Shot: What to Do Before and After PRP Treatment

At Smooth Synergy Medical Spa, NYC, we consider you an equal partner in the success of your Platelet-Rich Plasma (PRP) treatment. In order to achieve optimal results from The P-Shot (Priapus Shot), please review our Pre and Post-Care Instructions for the P-Shot: 


Two Weeks Before the P-Shot

  • Refrain from use of excessive or unnecessary blood thinners.


One Week Before the P-Shot

  • Use of any Nonsteroidal anti-inflammatory drugs (NSAIDs) including over-the-counter medications like Ibuprofen (Motrin, Aleve) and Aspirin, as well as prescription medications like Naproxen is not recommended, as these medications may interfere with platelet function.
  • Use Acetaminophen (Tylenol) for pain relief, when necessary.


Three Days Before the P-Shot

  • If you have a history of genital herpes, notify the physician, who will prescribe a course of antiviral prophylactic treatment.
  • Take a course of Arnica Homeopathic tablets until a day after treatment to decrease the occurrence of bruising.
  • Notify Smooth Synergy to reschedule, If between now and your appointment, you have an active outbreak of Human Papillomavirus (HPV) or genital herpes.

The Day of Your PRP Procedure

  • Comfort Measures:
    • Be sure to eat a small meal prior to treatment, as blood will be drawn.
    • A topical numbing cream can be applied before treatment.
    • If you elect to receive anti-anxiety medicine, such as Xanax, the physician will provide it to you on-site.
    • Pro Nox self-administered analgesic is available to reduce pain and anxiety.
    • If opting for anti-anxiety medication, arrange for transportation home following treatment.

P-Shot After Care

  • Allow up to two hours for anti-anxiety medication to wear off. Be sure you feel steady on your feet, before engaging in any activity.
  • Showering and cleansing the treatment area are allowed, once medication has worn off. A gentle cleanser may be used on the treatment area.
  • Refrain from strenuous exercise for 24 hours.
  • Comfort Measures:
    • Acetaminophen may be used for discomfort. Refrain from NSAIDs (see above) for seven days.
    • Antihistamines, like Benadryl and Zyrtec, may be used for minor itching.
    • For up to 48 hours following treatment, cool packs or ice can relieve minor discomfort and reduce swelling and bruising. Ice for a maximum of 20 minutes per hour. After 48 hours, switch to hot packs.
    • Arnica Gel may be used for bruising.
    • If extreme swelling or any unforeseen symptoms occur, please contact Smooth Synergy at 212-397-0111.

Post-Treatment Expectations

  • With the exception of strenuous exercise, you may return to normal activity including sexual intercourse after treatment.
  • Most side effects from the treatment should not be cause for alarm. Symptoms are usually minor and should subside in time, as a normal part of the healing process. They may be alleviated with simple measures, as described above.
  • Immediately following treatment, the treatment area may appear flushed, which usually subsides within several hours.
  • Mild tingling, swelling, soreness, and tenderness may occur for up to three days.
  • Bruising, particularly at the injection site, may last for several weeks.
  • If you are concerned about any aspect of your post-treatment recovery, please call Smooth Synergy at 212-397-0111.

Most men experience improved sensation immediately following the P-Shot. Additionally, collagen remodeling will continue for up to six months to deliver benefits that can include:

  • Lasting improvements in sexual performance
  • A larger, stronger and straighter penis
  • Firmer, more frequent erections
  • Increased circulation for a healthier penis
  • Increased sensation and pleasure
  • Enhancement of the results of Viagra or Cialis
  • May correct damage from diabetes


One treatment is recommended to start and re-evaluation is recommended after several months. Results may vary. Some men require yearly maintenance of the procedure.